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Your Ultimate Guide: Hyper-diluted Radiesse HDR


Hyder-Diluted Radiesse (HDR) is a popular, off-label use of the FDA-approved Radiesse filler that works as a bio-stimulant to build collagen almost anywhere on the body.


What Exactly is Hyper-Diluted Radiesse?


Radiesse is a well-established collagen stimulator used as a filler to volumize areas in the face such as cheekbones, jawline or chin. In recent years, studies have demonstrated an increased use in a hyper-diluted form. Hyper-diluted Calcium Hydroxylapatite (CaHa, also known as Radiesse) has been demonstrated to improve the quality of skin texture and firmness in both face and other areas of the body such as the neck, decolletage, buttocks, thighs, abdomen and arms.


This product is great to improve skin laxity as well as provide volume. HDR is a bio-stimulator for skin tightening as well as a volume replacement. The outcome will depend upon the concentration of the dilution and what area is being treated. Different ratios of CaHa to dilutant are determined after assessing the skin laxity and area of placement.


How does it work?


Fibroblasts are cells found in connective tissue which secrete collagen proteins that are used to maintain a structural framework for many tissues and also in wound healing. The particles in the injection solution, CaHa microspheres, stimulates the production of collagen already in the body, helping the body to build its own natural collagen. CaHa is secondary to a controlled inflammatory process that generates a predominantly fibroblastic reaction with replacement of the aqueous gel by a dense deposit of collagen. The main type of deposit is type 1 collagen, which is associated with improved mechanical properties of the skin. In studies, CaHa produced more type 1 collagen and elastin and resulted in a greater proliferation of fibroblasts compared to Hyaluronic Acid. CaHa also improved contractile function.

When does it start working and how long does it last?


Studies have shown Radiesse to be effective in increasing the production of type 1 collagen and elastin 7 months after injection and found that it improved neck and decolletage laxity after 2 sessions at 4 month intervals. Two and a half years after injection, even after complete absorption of the CaHA particles, participants demonstrated an increased of collagen on MRI imaging. Moreover, skin thickness improved by 50% after 3 months of application and was maintained in 91% of subjects during the 18-month evaluation period.


HDR begins producing collagen and elastin as early as 4-5 weeks after injection. Study participants reported an improvement in laxity and dermal thickness in the abdominal region, arms, and thighs as soon as 5 weeks after the procedure. For example, they observed a decrease in arm laxity after 2 treatment sessions separated a month apart. Because Radiesse helps the body make new collagen, one can expect results that last up to 18 months.


Who is a candidate?


For patients with mild to moderate laxity, HDR may be an excellent option. In fact, most adults are a good candidate for the procedures. There are a few exceptions: such as pregnancy or those with severe allergies, or who are allergic to lidocaine. This treatment will strengthen the skin and improve the appearance of wrinkles.


Can it treat cellulite?


Yes, HDR can absolutely be used to treat cellulite. By diluting Radiesse less, thereby making the solution thicker, practitioners can treat areas with moderate to severe dimples; the skin is plumped up with the thick solution, thereby reducing the appearance of dimpling.


Is it safe?


By using cannula technique, this off-label treatment can be performed safely, effectively, and precisely by trained medical practitioners.


How many treatments will I need?


One to 3 initial treatment sessions are typically needed to achieve the aesthetic effects desired. Maintenance is required every 12-18 months.


Does the treatment hurt?


HDR is mixed with lidocaine for a more comfortable treatment experience. Morevoer, practitioners skilled with advanced cannula methods can perform the treatment virtually painlessly.


Does Radiesse have any Risks or Side effects?


Radiesse injections are not dangerous or pose health risks for most people. The microspheres in the product are calcium-based, similar to minerals found within the body, and no allergy testing is needed for treatment due to high biocompatibility. As with any treatment, a review of your health history is always important. The side effects are as you would find with any dermal filler. There is a slight chance of swelling, bruising, or redness at the injection site. Any swelling or redness quickly fades, leaving only the smoothing effect of the Radiesse.

What are the benefits of using HDR?


HDR helps to offset volume loss in a short amount of time, with results appearing in 4 to 5 weeks. HDR can help reduce cellulite, correct acne-scarring and may reverse crepey-like skin. HDR is known for stimulating the regeneration of collagen and elastin, safely. It is a non-surgical and non-invasive alternative for these beauty concerns. This treatment is ideal for tackling the negative effects of aging on skin to provide a more youthful, refreshed look from the inside out.


If you live in Miami and your question is how to find "Hyperdiluted Radiesse near me", then your answer is at My Derma Clinic Medical Aesthetics in Pinecrest.


By: Vanessa Padron APRN-BC

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